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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CUX1 All Species: 7.58
Human Site: S1436 Identified Species: 13.89
UniProt: P39880 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P39880 NP_853530.2 1505 164273 S1436 G E G P A A P S S A P P P S N
Chimpanzee Pan troglodytes XP_527845 1515 165612 S1446 E G P A A R S S A P P P S N S
Rhesus Macaque Macaca mulatta XP_001114534 1791 194745 S1722 S S A P P P S S C S S S S S S
Dog Lupus familis XP_546939 1411 154543 H1342 C R A R D G A H R S S A L P S
Cat Felis silvestris
Mouse Mus musculus P53564 1515 165577 A1446 G A A R A G P A E R S S A L P
Rat Rattus norvegicus P53565 862 92341 R795 A R A G P A E R S S A L P S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506212 1543 168501 S1474 V S P V P S S S A P I S P S P
Chicken Gallus gallus XP_425393 1673 183755 S1604 S K E S S E K S S S V P S T S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_693902 1398 154481 G1329 P S A A S S P G L M M S V S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P10180 2175 233610 V2003 V T N P S A V V A A V A A A A
Honey Bee Apis mellifera XP_623857 1936 209316 P1826 V N P E W Q E P A R G A G D E
Nematode Worm Caenorhab. elegans Q9BL02 1273 143507 Q1206 S Q W A P D Y Q N R A G S V K
Sea Urchin Strong. purpuratus XP_780858 1460 163719 L1393 L R Q D N V K L Y E K I R F L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 83.1 56.2 N.A. 88.8 47.1 N.A. 44.3 77.4 N.A. 40.9 N.A. 23.3 23.7 22.3 29.1
Protein Similarity: 100 98.6 83.4 64.5 N.A. 91.8 50 N.A. 60 81.7 N.A. 55.4 N.A. 37.4 41 41 46.6
P-Site Identity: 100 26.6 20 0 N.A. 20 26.6 N.A. 20 20 N.A. 13.3 N.A. 20 0 0 0
P-Site Similarity: 100 46.6 33.3 13.3 N.A. 26.6 33.3 N.A. 33.3 53.3 N.A. 26.6 N.A. 40 6.6 13.3 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 39 24 24 24 8 8 31 16 16 24 16 8 8 % A
% Cys: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 0 0 0 8 8 8 0 0 0 0 0 0 0 8 0 % D
% Glu: 8 8 8 8 0 8 16 0 8 8 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 16 8 8 8 0 16 0 8 0 0 8 8 8 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % I
% Lys: 0 8 0 0 0 0 16 0 0 0 8 0 0 0 8 % K
% Leu: 8 0 0 0 0 0 0 8 8 0 0 8 8 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 8 8 0 0 0 0 % M
% Asn: 0 8 8 0 8 0 0 0 8 0 0 0 0 8 8 % N
% Pro: 8 0 24 24 31 8 24 8 0 16 16 24 24 8 24 % P
% Gln: 0 8 8 0 0 8 0 8 0 0 0 0 0 0 0 % Q
% Arg: 0 24 0 16 0 8 0 8 8 24 0 0 8 0 0 % R
% Ser: 24 24 0 8 24 16 24 39 24 31 24 31 31 39 31 % S
% Thr: 0 8 0 0 0 0 0 0 0 0 0 0 0 8 8 % T
% Val: 24 0 0 8 0 8 8 8 0 0 16 0 8 8 0 % V
% Trp: 0 0 8 0 8 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 8 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _